⚠ DRAFT 1.0 rev 1 — NOT FOR PUBLIC DISTRIBUTION — Work in progress · April 24 2026
⚠ Important Disclaimer — Please Read Before Using This Reference
This document is not a product comparison, ranking, or recommendation guide. It is an independent, volunteer-compiled resource intended for informational and educational purposes only. It does not constitute veterinary advice, medical guidance, treatment protocols, or feeding recommendations of any kind. All dietary decisions for dogs with copper-associated hepatopathy (CAH) or any other medical condition should be made in consultation with a licensed veterinarian or veterinary internal medicine specialist familiar with your dog's individual history, bloodwork, and clinical status.
All nutritional values are reported as provided by manufacturers via direct correspondence or official publications and may vary. No warranty, express or implied, is made regarding accuracy, completeness, or currency. Manufacturers may change formulations at any time without notice; values may differ between production batches, countries of distribution, or product sizes. Users are responsible for independently verifying all information prior to use.
Any interpretation of the data — including determination of suitability for a specific dog or condition — is the sole responsibility of the reader in consultation with a licensed veterinarian. No professional-client relationship is created through use of this document, and the compiler assumes no duty of care to any reader or user.
References to veterinary professionals or published research are provided for general context only and do not imply endorsement of this document or its contents. This reference is compiled for informational use primarily in Canada; product formulations and nutrient values may differ in other countries.
This reference was compiled by a private dog owner in Calgary, Alberta and is not affiliated with, endorsed by, or sponsored by any pet food manufacturer, veterinary organization, or regulatory body. No compensation was received from any brand listed. Use of this information is entirely at your own risk and discretion. To the fullest extent permitted by applicable law, the compiler assumes no duty of care and accepts no liability for any loss, injury, or outcome resulting from the use or reliance on this information.
How to Use This Reference
This document is intended to support informed discussions with a veterinarian — not to provide feeding recommendations. Copper values should be interpreted in the context of a dog's total daily caloric intake, individual medical history, and veterinary guidance.
Comparisons in this document are relative within the subset of products evaluated and do not represent a comprehensive ranking of all available dog foods. Highlighted products represent a subset of evaluated formulas and should not be interpreted as a ranked or recommended list. Lower or higher copper values do not determine suitability for any specific dog. Individual entries labeled as "lowest" or "highest" refer only to comparisons within a specific brand or evaluated subset and should not be interpreted as cross-market rankings.
Common misinterpretations to avoid: "Lowest copper" does not mean "best" or "recommended." Copper content alone does not determine diet suitability. mg/kg values are not directly comparable across products without caloric normalization — mg/Mcal is the preferred comparison metric. Absence of a product from this reference does not imply higher or lower copper content.
Copper level:
● Low <3 mg/Mcal
● Moderate 3–6 mg/Mcal
● High >6 mg/Mcal
Rx Prescription only
OTC Over-the-counter
Not in CA Not available in Canada
DC Discontinued
Copper level categorizations (low, moderate, high) are general reference ranges only and do not constitute recommendations or suitability assessments for any individual dog. Values labeled "lowest" or "highest" refer to comparisons among evaluated formulas based on available data only, and do not represent market-wide rankings. Absence of data for a given product or brand does not imply higher or lower copper content.
Prescription / Therapeutic Diets
Prescription Hepatic Diets Rx
Formulated for copper-restricted therapeutic use per manufacturer and veterinary guidance. All require a veterinary prescription.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg | Source |
| Royal Canin Canine Hepatic (dry) RxLabel max 7.2 mg/kg as-fed (~1.92 mg/Mcal) — actual content significantly lower per manufacturer confirmation. | 1.0 | ~3.7 as-fed | Royal Canin Canada · email Apr 16 2026 |
Purina Pro Plan Veterinary Diets — confirmed Apr 23 2026: no copper-restricted veterinary diet available in their lineup.
Honest Kitchen
Honest Kitchen — Wholemade Dehydrated OTC
Confirmed by Honest Kitchen email Apr 16 2026 · Add warm water, wait 3 minutes, serve · Lowest copper values among evaluated Honest Kitchen formulas
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | Source |
| Wholemade Grain Free Fish | 1.92 | 7.3 | HK · email Apr 16 2026 |
| Wholemade Whole Grain Turkey | 1.93 | 8.0 | HK · email Apr 16 2026 |
| Wholemade Grain Free Chicken | 2.29 | 9.0 | HK · email Apr 16 2026 |
| Wholemade Whole Grain Beef | 2.58 | 10.0 | HK · email Apr 16 2026 |
Honest Kitchen — Whole Food Clusters (baked) OTC
Values from Honest Kitchen Salsify product database Apr 16 2026 · Separate product line — significantly higher copper than Wholemade dehydrated
⚠ Clusters are a distinct product from Wholemade. Beef-based Clusters are substantially higher in copper. Gourmet GF Beef at ~10.36 mg/Mcal exceeds the EU/FEDIAF maximum of 6.25 mg/Mcal. Suitability should be assessed with a veterinarian for copper-restricted dogs.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | Source |
| Essential Whole Grain Turkey & Chicken | ~3.61 | 13.4 | HK Salsify · Apr 16 2026 |
| Gourmet Whole Grain Chicken (adult) | ~3.74 | 15.0 | HK Salsify · Apr 16 2026 |
| Gourmet GF Chicken Puppy | ~4.45 | 18.0 | HK Salsify · Apr 16 2026 |
| Essential Whole Grain Chicken | ~4.52 | 16.4 | HK Salsify · Apr 16 2026 |
| Gourmet WG Chicken Small Breed / Puppy | ~4.53–4.57 | 18.0 | HK Salsify · Apr 16 2026 |
| Gourmet GF Turkey | ~4.90 | 19.0 | HK Salsify · Apr 16 2026 |
| Gourmet GF Chicken (adult) | ~5.19 | 20.0 | HK Salsify · Apr 16 2026 |
| Gourmet WG Beef (adult) | ~5.14 | 21.0 | HK Salsify · Apr 16 2026 |
| Essential WG Beef & Chicken | ~5.42 | 20.9 | HK Salsify · Apr 16 2026 |
| WG Beef, Oat & TurkeyBeef liver — higher copper relative to other evaluated formulas; suitability should be assessed with a veterinarian. | ~7.56 | 29.0 | HK Salsify · Apr 16 2026 |
| Gourmet GF Beef Small BreedBeef liver — higher copper relative to other evaluated formulas; suitability should be assessed with a veterinarian. | ~7.50 | 30.0 | HK Salsify · Apr 16 2026 |
| Gourmet GF Beef (adult)⚠ Exceeds EU/FEDIAF maximum of 6.25 mg/Mcal. | ~10.36 | 40.0 | HK Salsify · Apr 16 2026 |
Nature's Logic Distinction
Nature's Logic Distinction Not in CA OTC
Not available in Canada · Values from natureslogic.com/distinction product pages Apr 16 2026 · No added synthetic vitamins or minerals
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Distinction Fowl (Chicken/Turkey/Duck) | ~1.88 | 7.6 | natureslogic.com · Apr 16 2026 |
| Distinction Chicken | ~1.89 | 7.2 | natureslogic.com · Apr 16 2026 |
| Distinction Sardine (no liver) | ~2.24 | 7.4 | natureslogic.com · Apr 16 2026 |
| Distinction Red (Beef/Pork/Lamb)Contains pork liver — higher copper relative to other Distinction formulas. | ~2.75 | 11.0 | natureslogic.com · Apr 16 2026 |
| Distinction Land & Sea (Beef/Sardine)Contains pork liver — elevated. | ~2.85 | 12.7 | natureslogic.com · Apr 16 2026 |
| Distinction BeefBeef liver drives copper higher relative to other evaluated formulas. | ~4.15 | 15.1 | natureslogic.com · Apr 16 2026 |
| Distinction Pork⚠ Exceeds EU/FEDIAF maximum. Pork liver is highest-copper organ meat among evaluated ingredients; suitability should be assessed with a veterinarian. | ~6.67 | 24.8 | natureslogic.com · Apr 16 2026 |
Voyager
Voyager Dog Food Not in CA OTC
Not available in Canada · Zero added synthetic copper · Zinc added as natural copper chelator · Voyager recommends Nature's Logic Distinction as Canadian alternative
References to veterinary professionals associated with this brand are provided for general context only and do not imply endorsement of this document or its contents.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | Source |
| Wholesome Pork | 2.00 | 8.0 | Voyager · email Apr 14 2026 |
| Wholesome Ocean Pollock | 2.50 | 8.2 | Voyager · email Apr 14 2026 |
| High Performance Chicken | 2.60 | 10.1 | Voyager · email Apr 14 2026 |
| Wholesome Farm Chicken | 2.70 | 9.2 | Voyager · email Apr 14 2026 |
| Sensitive Skin & Stomach SalmonOutlier — salmon naturally higher in copper. Higher relative to other Voyager formulas among those evaluated. | 5.30 | 18.4 | Voyager · email Apr 14 2026 |
Royal Canin Canada
Royal Canin Canada — OTC Formulas OTC
Lower copper values within the evaluated subset of OTC products in Canada (based on available data) per Royal Canin Canada Apr 2026
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg | Source |
| West Highland White Terrier Adult DCNo longer available in Canada per Royal Canin Canada Apr 2026. Listed for reference only. | 2.5 | — | RC Canada · email Apr 16 2026 |
| Dachshund Adult (lower copper value among evaluated OTC products in Canada — based on available data — not breed-specific) | 2.6 | — | RC Canada · email Apr 16 2026 |
| Labrador Adult | 3.0 | — | RC Canada · email Apr 16 2026 |
| Labrador Retriever Puppy | 3.0 | — | RC Canada · email Apr 16 2026 |
Open Farm
Open Farm OTC
Two lowest-copper formulas confirmed Apr 2026 · Copper source is chelated proteinate · Other Open Farm recipes unconfirmed
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Epic Blend Salmon & Superfood | ~3.4 | 12.40 | Open Farm · email Apr 13 2026 |
| Epic Blend Chicken & Superfood | ~3.8 | 13.60 | Open Farm · email Apr 13 2026 |
ORIJEN
ORIJEN OTC
Champion Petfoods · email Apr 14–15 2026 · Total copper confirmed including native ingredient copper · Lowest copper values among evaluated ORIJEN formulas
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Senior | 3.7 | 15.58 | Champion · email Apr 14 2026 |
| Adult Large Breed | 4.0 | 16.82 | Champion · email Apr 15 2026 |
| Six FishHigher copper relative to other evaluated ORIJEN formulas; suitability should be assessed with a veterinarian. | 4.6 | 20.31 | Champion · email Apr 15 2026 |
ACANA Kibble
ACANA Kibble OTC
Champion Petfoods · email Apr 14 2026 · Total copper confirmed including native ingredient copper · Lowest copper values among evaluated ACANA kibble formulas
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Healthy Grains Large Breed | ~4.1 | 14.5 | Champion · email Apr 14 2026 |
| Healthy Grains Free Run Poultry | ~4.3 | 15.0 | Champion · email Apr 14 2026 |
| Senior | ~4.3 | 15.20 | Champion · email Apr 14 2026 |
| Healthy Grains Sea to Stream | ~4.4 | 15.34 | Champion · email Apr 14 2026 |
ACANA Freeze-Dried Patties & Morsels
ACANA Freeze-Dried Patties & Morsels OTC
Champion Petfoods · email Apr 20 2026 · All values as-fed basis · mg/Mcal estimated using ~4,500 kcal/kg
⚠ ACANA Freeze-Dried copper values are significantly higher than ACANA kibble. Owners switching from ACANA kibble to ACANA freeze-dried, perceived as a "healthier" option, may experience higher copper intake depending on formulation and feeding amount.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal (est.) | mg/kg as-fed | Source |
| Freeze-Dried Free-Run Turkey (lowest within the evaluated subset of ACANA freeze-dried formulas) | ~8.5 | 38.40 | Champion · email Apr 20 2026 |
| Freeze-Dried Free-Run Chicken | ~9.0 | 40.40 | Champion · email Apr 20 2026 |
| Freeze-Dried Free-Run Duck | ~9.3 | 41.89 | Champion · email Apr 20 2026 |
| Freeze-Dried BeefHighest among evaluated ACANA freeze-dried formulas. | ~9.8 | 44.30 | Champion · email Apr 20 2026 |
Wellness Pet Company
Wellness Pet Company OTC
Comprehensive response Apr 2026 — 50+ formulas provided · Values are total finished product copper · Complete Health grain-inclusive formulas are the lowest within the evaluated subset of Wellness formulas
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Complete Health Chicken & Oatmeal | ~3.2 | 11.73 | Wellness · email Apr 17 2026 |
| Complete Health Healthy Weight Chicken & Peas | ~3.3 | 11.98 | Wellness · email Apr 17 2026 |
| Complete Health Senior Small Breed Turkey & Pea | ~3.3 | 12.14 | Wellness · email Apr 17 2026 |
| Complete Health Beef & Barley | ~3.4 | 12.38 | Wellness · email Apr 17 2026 |
| Complete Health Lamb & Barley | ~3.4 | 12.42 | Wellness · email Apr 17 2026 |
| Complete Health Senior Chicken & Barley | ~3.4 | 12.45 | Wellness · email Apr 17 2026 |
| CORE Wholesome Grains Ocean | ~3.4 | 12.48 | Wellness · email Apr 17 2026 |
| CORE Digestive Health Whitefish Brown Rice | ~3.4 | 12.52 | Wellness · email Apr 17 2026 |
| CORE Small Breed Healthy Weight | ~3.6 | 13.15 | Wellness · email Apr 17 2026 |
| Complete Health Small Breed Turkey & Oatmeal | ~3.7 | 13.78 | Wellness · email Apr 17 2026 |
| Complete Health Large Breed Chicken & Brown Rice | ~4.0 | 14.93 | Wellness · email Apr 17 2026 |
| Complete Health Whitefish & Sweet PotatoFish-based — higher copper relative to other Complete Health grained formulas among those evaluated. | ~4.9 | 18.17 | Wellness · email Apr 17 2026 |
| CORE SeniorHigher copper relative to other evaluated Wellness formulas; suitability should be assessed with a veterinarian. | ~5.9 | 21.73 | Wellness · email Apr 17 2026 |
| CORE Wholesome Grains OriginalHigher copper; suitability should be assessed with a veterinarian. | ~6.0 | 22.26 | Wellness · email Apr 17 2026 |
| CORE Large Breed PuppyVery high; suitability should be assessed with a veterinarian. | ~6.7 | 24.71 | Wellness · email Apr 17 2026 |
| CORE Small Breed PuppyHighest among evaluated Wellness formulas; suitability should be assessed with a veterinarian. | ~9.7 | 35.87 | Wellness · email Apr 17 2026 |
IAMS
IAMS OTC
Two lowest adult formulas confirmed Apr 2026 · IAMS owned by Mars Inc.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Proactive Health Adult Large Breed | ~3.7 | 13.10 | IAMS · email Apr 17 2026 |
| Proactive Health Adult Beef & Rice | ~3.7 | 13.13 | IAMS · email Apr 17 2026 |
Purina Pro Plan
Purina Pro Plan OTC
All 8 requested formulas confirmed · Harison, Purina Canada · emails Apr 17 & Apr 21 2026 · Values are mg/1000 kcal as provided directly by Purina
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | Source |
| Complete Essentials Adult Chicken & Rice | 3.3 | Purina · email Apr 17 2026 |
| Sport Performance 30/20 Chicken & Rice | 3.7 | Purina · email Apr 17 2026 |
| Adult Small Breed Chicken & Rice | 3.9 | Purina · email Apr 21 2026 |
| Adult Large Breed Chicken & Rice | 4.0 | Purina · email Apr 21 2026 |
| Bright Mind Adult 7+ Chicken & Rice | 4.1 | Purina · email Apr 21 2026 |
| Complete Essentials Adult Beef & Rice | 4.4 | Purina · email Apr 21 2026 |
| Sensitive Skin & Stomach Adult Salmon & Rice | 4.6 | Purina · email Apr 21 2026 |
| Weight Management Adult Chicken & Rice | 5.0 | Purina · email Apr 21 2026 |
Blue Buffalo
Blue Buffalo OTC
Two lowest-copper formulas confirmed Apr 2026 · Blue Buffalo owned by General Mills
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | Source |
| Freedom Grain Free Adult Healthy Weight Chicken (lowest within the evaluated subset of Blue Buffalo formulas) | ~3.50 | 11.50 | Blue Buffalo · email Apr 17 2026 |
| Life Protection Adult Healthy Weight Chicken & Brown Rice | ~3.62 | 11.80 | Blue Buffalo · email Apr 17 2026 |
Diamond Pet Foods / Kirkland / Taste of the Wild
Diamond / Kirkland Signature / Taste of the Wild OTC
Diamond Pet Foods email Apr 20 2026 · All three brands manufactured by Diamond Pet Foods · 17 mg/kg DM confirmed total · mg/Mcal estimated ~4.3–4.7
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal (est.) | mg/kg DM | Source |
| All Diamond / Kirkland Signature / Taste of the Wild formulasSingle confirmed value applies across all formulations for all three brands. Copper is both added (premix) and naturally occurring. | ~4.3–4.7 | 17 | Diamond Pet Foods · email Apr 20 2026 |
Primal Pet Foods
Primal Pet Foods — Kibble in the Raw OTC
Official website primalpetfoods.com · Typical Analysis per product page · No added synthetic vitamins or minerals · Available in Canada
Key finding (based on available data): protein source drives copper level significantly — beef formulas are substantially higher than chicken or fish-based formulas among those evaluated.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | Source |
| Kibble in the Raw — Fish & Pork Recipe | 1.92 | 8.19 | primalpetfoods.com · Apr 20 2026 |
| Kibble in the Raw — Chicken Recipe | 2.40 | 10.25 | primalpetfoods.com · Apr 20 2026 |
| Kibble in the Raw — Small Breed Chicken | 2.40 | — | primalpetfoods.com · Apr 20 2026 |
| Kibble in the Raw — Puppy Recipe | 3.43 | — | primalpetfoods.com · Apr 20 2026 |
| Kibble in the Raw — Beef RecipeSubstantially higher than other Kibble in the Raw formulas due to beef liver; suitability should be assessed with a veterinarian. | 9.49 | 40.53 | primalpetfoods.com · Apr 20 2026 |
Primal Pet Foods — Freeze-Dried Raw Nuggets OTC
Official website primalpetfoods.com · Typical Analysis per product page
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | Source |
| Freeze-Dried Nuggets — Chicken | 2.00 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — Turkey & Sardine | 2.12 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — Rabbit | 2.36 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — Pork | 2.52 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — Duck | 2.61 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — Venison | 4.07 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — LambHigher copper; suitability should be assessed with a veterinarian. | 8.99 | primalpetfoods.com · Apr 20 2026 |
| Freeze-Dried Nuggets — BeefHighest among evaluated Primal Nugget formulas; suitability should be assessed with a veterinarian. | 10.80 | primalpetfoods.com · Apr 20 2026 |
Primal Pet Foods — Freeze-Dried Scoopable Pronto OTC
Official website primalpetfoods.com
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | Source |
| Pronto FD — Chicken | 2.19 | primalpetfoods.com · Apr 20 2026 |
| Pronto FD — Pork | 2.91 | primalpetfoods.com · Apr 20 2026 |
| Pronto FD — Lamb | 3.68 | primalpetfoods.com · Apr 20 2026 |
| Pronto FD — Puppy | 3.84 | primalpetfoods.com · Apr 20 2026 |
| Pronto FD — BeefHighest among evaluated Pronto FD formulas; suitability should be assessed with a veterinarian. | 13.05 | primalpetfoods.com · Apr 20 2026 |
Primal Pet Foods — Frozen Raw (Nuggets, Patties, Scoopable Pronto) OTC
Official website primalpetfoods.com · Nuggets, Patties, and Frozen Pronto share identical values per protein
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | Source |
| Frozen — Chicken (all formats) | 2.14 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Turkey & Sardine (all formats) | 2.16 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Rabbit (all formats) | 2.34 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Pork (all formats) | 2.47 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Duck (all formats) | 2.62 | primalpetfoods.com · Apr 20 2026 |
| Frozen Pronto — Puppy | 3.36 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Venison (Nuggets/Patties) | 4.60–4.80 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Beef (all formats)Higher copper; suitability should be assessed with a veterinarian. | 8.66 | primalpetfoods.com · Apr 20 2026 |
| Frozen — Lamb (all formats)Higher copper; suitability should be assessed with a veterinarian. | 9.06 | primalpetfoods.com · Apr 20 2026 |
ZIWI Peak
ZIWI Peak — Air-Dried Original Series OTC
Values from ziwipets.com/pages/typical-analysis · mg/Mcal calculated from published kcal/kg
⚠ No formula in this line falls within the "low" range defined above. Tripe & Lamb and Lamb are substantially higher due to organ content. Suitability should be assessed with a veterinarian before using any ZIWI product for copper-restricted dogs.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | mg/kg DM | kcal/kg | Source |
| Chicken | 4.80 | 24 | 19 | 5000 | ziwipets.com · Apr 21 2026 |
| Venison | 4.95 | 23 | 20 | 4650 | ziwipets.com · Apr 21 2026 |
| Beef | 5.31 | 26 | 22 | 4900 | ziwipets.com · Apr 21 2026 |
| Mackerel & Lamb | 5.78 | 26 | 23 | 4500 | ziwipets.com · Apr 21 2026 |
| LambHigher copper due to organ content; suitability should be assessed with a veterinarian. | 7.88 | 39 | 32 | 4950 | ziwipets.com · Apr 21 2026 |
| Tripe & LambHighest among evaluated air-dried ZIWI formulas; suitability should be assessed with a veterinarian. | 10.65 | 49 | 42 | 4600 | ziwipets.com · Apr 21 2026 |
ZIWI Peak — Steam & Dried OTC
Values from ziwipets.com/pages/typical-analysis · Lowest copper values among evaluated ZIWI lines
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | mg/kg DM | kcal/kg | Source |
| Steam & Dried — Beef with Pumpkin | 3.41 | 15 | 13 | 4400 | ziwipets.com · Apr 21 2026 |
| Steam & Dried — Chicken with Orchard Fruits | 4.65 | 20 | 19 | 4300 | ziwipets.com · Apr 21 2026 |
| Steam & Dried — Lamb with Green Vegetables | 5.00 | 22 | 20 | 4400 | ziwipets.com · Apr 21 2026 |
ZIWI Peak — Canned Wet Food OTC
Values from ziwipets.com/pages/typical-analysis · Moisture ~74–77%
⚠ Canned wet food as-fed copper values appear lower than air-dried due to high moisture content (~75%). DM values and mg/Mcal are the appropriate comparison metrics across formats.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | mg/kg DM | kcal/kg | Source |
| Canned — Chicken | 3.27 | 4 | 13 | 1225 | ziwipets.com · Apr 21 2026 |
| Canned — Venison | 4.88 | 5 | 18 | 1025 | ziwipets.com · Apr 21 2026 |
| Canned — Beef | 5.33 | 6 | 21 | 1125 | ziwipets.com · Apr 21 2026 |
| Canned — Lamb | 5.83 | 7 | 24 | 1200 | ziwipets.com · Apr 21 2026 |
| Canned — Mackerel & LambHigher copper; suitability should be assessed with a veterinarian. | 6.67 | 7 | 25 | 1050 | ziwipets.com · Apr 21 2026 |
| Canned — Tripe & LambHighest among evaluated canned ZIWI formulas; suitability should be assessed with a veterinarian. | 8.00 | 8 | 31 | 1000 | ziwipets.com · Apr 21 2026 |
Nutrience
Nutrience (Hagen Canada) OTC
Hagen Canada · email Apr 22 2026 · Canadian brand · On-staff Companion Animal Nutritionist · All three metrics provided · Zinc:copper balance monitored in formulation
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | mg/kg DM | Source |
| Care Sensitive Skin & Stomach (lowest within the evaluated subset of Nutrience formulas) | 3.2 | 11.1 | 12.1 | Nutrience/Hagen · email Apr 22 2026 |
| Care Weight Management | 3.5 | 11.8 | 12.4 | Nutrience/Hagen · email Apr 22 2026 |
| Infusion Healthy Adult | 3.6 | 13.4 | 14.5 | Nutrience/Hagen · email Apr 22 2026 |
| Infusion Adult Large Breed | 3.6 | 13.7 | 14.8 | Nutrience/Hagen · email Apr 22 2026 |
| Infusion Healthy Senior | 3.6 | 13.6 | 14.7 | Nutrience/Hagen · email Apr 22 2026 |
| SubZero Northern Lakes | 3.7 | 13.3 | 14.5 | Nutrience/Hagen · email Apr 22 2026 |
| SubZero Prairie Red | 3.8 | 13.5 | 14.7 | Nutrience/Hagen · email Apr 22 2026 |
| Infusion Healthy Puppy | 3.9 | 14.6 | 15.9 | Nutrience/Hagen · email Apr 22 2026 |
| SubZero Canadian Pacific | 4.1 | 14.8 | 16.1 | Nutrience/Hagen · email Apr 22 2026 |
| SubZero Fraser Valley | 4.4 | 16.1 | 17.5 | Nutrience/Hagen · email Apr 22 2026 |
FirstMate
FirstMate OTC
Wendy Vandersteen PhD, Manager of Research and Development · FirstMate · email Apr 20–22 2026 · Canadian family-owned manufacturer
All FirstMate formulas formulated with copper at a minimum of 12.4 mg/kg DM. Natural variation typically 12–25 mg/kg DM, average 13.7 mg/kg DM. Per-formula breakdown not available — manufacturer confirmed no single formula stands out as lower; variation reflects both protein source and carbohydrate ingredients.
Estimated mg/Mcal: At typical kibble caloric density of ~3,500–4,000 kcal/kg, the average of 13.7 mg/kg DM corresponds to approximately 3.4–3.9 mg/Mcal. Based on available information, estimated values fall within the moderate range; per-formula confirmation is not available.
Fromm Family
Fromm Classic — Dry OTC
Values from frommfamily.com typical analysis per recipe page · Grain-inclusive chicken and fish-based formulas
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Classic Adult Whitefish & Rice (lowest within the evaluated subset of Fromm dry formulas) | 3.47 | 12.20 | 3,521 | frommfamily.com · Apr 23 2026 |
| Classic Adult Large & Giant Breed | 3.95 | 14.00 | 3,547 | frommfamily.com · Apr 23 2026 |
| Classic Adult | 3.64 | 13.52 | 3,718 | frommfamily.com · Apr 23 2026 |
| Classic Mature Adult | 4.05 | 14.43 | 3,563 | frommfamily.com · Apr 23 2026 |
Fromm Gold Nutritionals — Dry OTC
Values from frommfamily.com typical analysis per recipe page · Grain-inclusive line — substantially lower in copper than Heartland Gold grain-free line
Key finding (based on available data): Fromm Gold grain-inclusive line is substantially lower in copper than Fromm Heartland Gold grain-free line. Owners switching to grain-free, perceived as a "healthier" option, may experience higher copper intake depending on formulation and feeding amount.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Puppy Gold | 3.02 | 11.64 | 3,849 | frommfamily.com · Apr 23 2026 |
| Small Breed Adult Gold | 3.13 | 11.91 | 3,797 | frommfamily.com · Apr 23 2026 |
| Adult Gold | 3.22 | 12.06 | 3,735 | frommfamily.com · Apr 23 2026 |
| Large Breed Puppy Gold | 3.35 | 12.14 | 3,625 | frommfamily.com · Apr 23 2026 |
| Large Breed Adult Gold | 3.47 | 12.36 | 3,561 | frommfamily.com · Apr 23 2026 |
| Reduced Activity & Senior Gold | 3.53 | 12.57 | 3,561 | frommfamily.com · Apr 23 2026 |
| Adult Gold with Ancient Grains | 3.59 | 13.30 | 3,702 | frommfamily.com · Apr 23 2026 |
| Weight Management Gold | 4.23 | 13.72 | 3,241 | frommfamily.com · Apr 23 2026 |
Fromm Gold Coast — Dry (Grain-Free Fish) OTC
Values from frommfamily.com typical analysis per recipe page · Grain-free fish-based formula — higher than Gold grain-inclusive line
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Gold Coast Weight ManagementContains chicken liver — higher than Gold grain-inclusive line despite fish-primary formula. | 5.22 | 17.20 | 3,297 | frommfamily.com · Apr 23 2026 |
Fromm Four-Star Nutritionals — Dry OTC
Values from frommfamily.com typical analysis per recipe page · Grain-free and grain-inclusive formulas · Sorted low to high
Fish-based Four-Star formulas are substantially lower in copper than beef/lamb/pork-based formulas among those evaluated. Beef + pork liver combination in Rancherosa and Pork & Applesauce drives values above EU/FEDIAF maximum.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Salmon À La Veg (grain-inclusive fish) | 3.98 | 14.97 | 3,761 | frommfamily.com · Apr 23 2026 |
| Whitefish & Potato (grain-inclusive fish — pork liver) | 4.12 | 14.20 | 3,446 | frommfamily.com · Apr 23 2026 |
| Salmon Tunalini (grain-free fish) | 4.24 | 15.50 | 3,658 | frommfamily.com · Apr 23 2026 |
| Game Bird (grain-free turkey/fowl) | 4.47 | 16.60 | 3,709 | frommfamily.com · Apr 23 2026 |
| Trout & Whitefish (grain-inclusive fish — pork liver) | 4.53 | 16.80 | 3,706 | frommfamily.com · Apr 23 2026 |
| Surf & Turf (grain-free salmon/chicken) | 4.54 | 17.20 | 3,789 | frommfamily.com · Apr 23 2026 |
| Zealambder (grain-inclusive lamb — lamb+pork liver) | 5.19 | 19.10 | 3,681 | frommfamily.com · Apr 23 2026 |
| Pork & Peas (grain-free pork — pork liver) | 5.48 | 20.23 | 3,695 | frommfamily.com · Apr 23 2026 |
| Lamb & Lentil (grain-free lamb — pork+lamb liver) | 5.61 | 21.10 | 3,757 | frommfamily.com · Apr 23 2026 |
| Beef Frittata Veg (grain-free beef — beef+pork liver)Exceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.42 | 24.17 | 3,765 | frommfamily.com · Apr 23 2026 |
| Rancherosa (grain-free beef/pork/trout/lamb — pork liver)Exceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.85 | 24.83 | 3,626 | frommfamily.com · Apr 23 2026 |
| Pork & Applesauce (grain-inclusive pork — pork liver)Highest among evaluated Four-Star dry formulas. Exceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 7.29 | 26.33 | 3,613 | frommfamily.com · Apr 23 2026 |
Fromm Heartland Gold — Dry (Grain-Free Red Meat) OTC
Values from frommfamily.com typical analysis per recipe page · Grain-free red meat formulas — substantially higher copper than Gold grain-inclusive line
⚠ Heartland Gold grain-free formulas are substantially higher in copper than Fromm Gold grain-inclusive formulas — approximately double in some cases. Three of four formulas exceed or approach the EU/FEDIAF maximum of 6.25 mg/Mcal. Pork and beef liver ingredients drive values higher. Suitability should be assessed with a veterinarian for copper-restricted dogs.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Heartland Gold Large Breed Puppy | 5.85 | 20.97 | 3,583 | frommfamily.com · Apr 23 2026 |
| Heartland Gold Large Breed AdultApproaches EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.51 | 22.53 | 3,462 | frommfamily.com · Apr 23 2026 |
| Heartland Gold AdultExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.90 | 25.10 | 3,637 | frommfamily.com · Apr 23 2026 |
| Heartland Gold PuppyHighest among evaluated Heartland Gold dry formulas. Exceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 7.37 | 27.70 | 3,757 | frommfamily.com · Apr 23 2026 |
Fromm Nutritionals — Dry (Functional Line) OTC
Values from frommfamily.com typical analysis per recipe page · Newer functional/specialty dry line
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Digestive Support Low Fat Chicken & Oatmeal | 3.95 | 13.13 | 3,326 | frommfamily.com · Apr 23 2026 |
| Mobility Chicken & Whole Oats | 4.07 | 14.40 | 3,538 | frommfamily.com · Apr 23 2026 |
| Sensitive Skin & Stomach Salmon & Whole Oats | 4.56 | 15.80 | 3,465 | frommfamily.com · Apr 23 2026 |
Fromm — Wet / Canned (Selected formulas) OTC
Values from frommfamily.com typical analysis per recipe page · As-fed basis · High moisture content — see data notes · Sorted low to high
Note: Wet food as-fed copper values reflect high moisture content (~75–84%). mg/Mcal is the appropriate comparison metric. Beef liver and lamb liver in several formulas drive copper substantially higher. Venison & Beef Pâté at 22.33 mg/Mcal is the highest confirmed value in this entire reference.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| Diner Breakfast Maddie's Morning Hash Beef & Sweet Potato | 3.43 | 3.50 | 1,021 | frommfamily.com · Apr 23 2026 |
| Frommbalaya Chicken, Vegetable & Rice Stew | 4.17 | 3.28 | 786 | frommfamily.com · Apr 23 2026 |
| Frommbalaya Turkey, Vegetable & Rice Stew | 4.51 | 3.55 | 788 | frommfamily.com · Apr 23 2026 |
| Frommbo Gumbo Beef Sausage Stew | 4.59 | 4.10 | 893 | frommfamily.com · Apr 23 2026 |
| Frommbalaya Pork, Vegetable & Rice Stew | 4.98 | 3.91 | 785 | frommfamily.com · Apr 23 2026 |
| Adult Chicken & Rice Pâté (Classics) | 5.12 | 5.57 | 1,088 | frommfamily.com · Apr 23 2026 |
| Frommbo Gumbo Pork Sausage Stew | 5.47 | 4.86 | 889 | frommfamily.com · Apr 23 2026 |
| Chicken Pâté | 5.35 | 6.07 | 1,134 | frommfamily.com · Apr 23 2026 |
| Diner Classics Charlie's Chicken Pot Pie Pâté | 5.66 | 5.50 | 971 | frommfamily.com · Apr 23 2026 |
| Salmon & Chicken Pâté | 5.73 | 6.03 | 1,053 | frommfamily.com · Apr 23 2026 |
| Diner Specials Chicken Canine Bleu | 5.73 | 5.57 | 1,088 | frommfamily.com · Apr 23 2026 |
| Chicken & Rice Pâté | 5.81 | 5.83 | 1,004 | frommfamily.com · Apr 23 2026 |
| Diner Classics Paula's Chicken & Pumpkin Pâté | 5.87 | 5.80 | 988 | frommfamily.com · Apr 23 2026 |
| Adult Turkey & Rice Pâté (Classics) | 5.90 | 6.04 | 1,023 | frommfamily.com · Apr 23 2026 |
| Puppy Chicken & Salmon Pâté (Classics) | 5.93 | 6.30 | 1,063 | frommfamily.com · Apr 23 2026 |
| Chicken & Sweet Potato Pâté | 5.98 | 6.07 | 1,014 | frommfamily.com · Apr 23 2026 |
| Diner Breakfast Betty's Biscuits & Gravy Pork & Eggs | 5.94 | 5.08 | 858 | frommfamily.com · Apr 23 2026 |
| Frommbo Gumbo Chicken Sausage StewApproaches EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 5.98 | 4.61 | 771 | frommfamily.com · Apr 23 2026 |
| Turkey & Pumpkin PâtéExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.08 | 6.80 | 1,119 | frommfamily.com · Apr 23 2026 |
| Turkey, Duck & Sweet Potato PâtéExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.13 | 6.90 | 1,126 | frommfamily.com · Apr 23 2026 |
| Chicken & Duck PâtéExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.17 | 6.08 | 985 | frommfamily.com · Apr 23 2026 |
| Seafood Medley PâtéExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.28 | 6.12 | 974 | frommfamily.com · Apr 23 2026 |
| Turkey PâtéExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.45 | 6.63 | 1,028 | frommfamily.com · Apr 23 2026 |
| Whitefish & Lentil PâtéExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.63 | 5.88 | 887 | frommfamily.com · Apr 23 2026 |
| Four-Star Shredded Beef in GravyHigher copper; suitability should be assessed with a veterinarian. | 7.55 | 5.63 | 735 | frommfamily.com · Apr 23 2026 |
| Immunity Supplement Pâté (intermittent/supplemental only)Supplemental product only; suitability should be assessed with a veterinarian. | 7.47 | 7.10 | 950 | frommfamily.com · Apr 23 2026 |
| Four-Star Shredded Turkey in GravyHigher copper; suitability should be assessed with a veterinarian. | 8.21 | 6.10 | 743 | frommfamily.com · Apr 23 2026 |
| Duck À La Veg PâtéHigher copper; suitability should be assessed with a veterinarian. | 8.46 | 8.90 | 1,052 | frommfamily.com · Apr 23 2026 |
| Four-Star Shredded Pork in GravyHigher copper; suitability should be assessed with a veterinarian. | 8.70 | 6.50 | 747 | frommfamily.com · Apr 23 2026 |
| Diner Breakfast Sam's Steak & EggsLow kcal/kg drives mg/Mcal high; suitability should be assessed with a veterinarian. | 9.01 | 5.30 | 588 | frommfamily.com · Apr 23 2026 |
| Four-Star Shredded Chicken in GravyHighest among evaluated Four-Star wet formulas; suitability should be assessed with a veterinarian. | 9.54 | 6.40 | 671 | frommfamily.com · Apr 23 2026 |
| Diner Specials Slow-Cooked Pulled PorkHigher copper; suitability should be assessed with a veterinarian. | 9.20 | 6.50 | 707 | frommfamily.com · Apr 23 2026 |
| Diner Favorites Bud's Beef & Broccoli StewBeef liver drives copper very high; suitability should be assessed with a veterinarian. | 9.80 | 7.50 | 765 | frommfamily.com · Apr 23 2026 |
| Lamb PâtéLamb liver drives copper very high; suitability should be assessed with a veterinarian. | 12.87 | 13.63 | 1,107 | frommfamily.com · Apr 23 2026 |
| Venison & Lentil PâtéBeef liver drives copper very high; suitability should be assessed with a veterinarian. | 12.97 | 12.70 | 979 | frommfamily.com · Apr 23 2026 |
| Beef & Sweet Potato PâtéBeef liver — very high; suitability should be assessed with a veterinarian. | 15.03 | 14.13 | 940 | frommfamily.com · Apr 23 2026 |
| Beef & Barley PâtéBeef liver — very high; suitability should be assessed with a veterinarian. | 15.17 | 14.33 | 945 | frommfamily.com · Apr 23 2026 |
| Venison & Beef PâtéHighest among all evaluated Fromm wet formulas. Beef liver extremely high; suitability should be assessed with a veterinarian. | 22.33 | 20.30 | 909 | frommfamily.com · Apr 23 2026 |
Bonnihill Farms by Fromm — Frozen Sous Vide OTC
Values from frommfamily.com typical analysis per recipe page · Sous vide cooked frozen format · mg/Mcal provided directly as mg per 100 kcal ME × 10
⚠ BeefiBowls is extremely high in copper due to beef liver as the third ingredient. ChickiBowls contains chicken liver — also high. TurkiBowls contains turkey liver. All three formulas require careful consideration for copper-restricted dogs; suitability should be assessed with a veterinarian.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg as-fed | kcal/kg | Source |
| TurkiBowls Turkey RecipeTurkey liver drives copper higher; suitability should be assessed with a veterinarian. | 6.50 | 8.08 | 1,239 | frommfamily.com · Apr 23 2026 |
| ChickiBowls Chicken RecipeChicken liver — higher copper; suitability should be assessed with a veterinarian. | 8.30 | 8.80 | 1,058 | frommfamily.com · Apr 23 2026 |
| BeefiBowls Beef RecipeBeef liver as third ingredient — extremely high copper; suitability should be assessed with a veterinarian. | 14.80 | 15.00 | 1,012 | frommfamily.com · Apr 23 2026 |
Petcurean
Petcurean (Now Fresh / GO! Solutions / Gather / Summit) OTC
Emily Thompson-Cory, Petcurean Customer Care · email Apr 21 2026 · Canadian company · Reports both supplemented and naturally occurring copper
Petcurean note: Companies vary in how they report copper values. Some disclose only the supplemented amount while others report both supplemented and naturally occurring. Petcurean reports both. When comparing values across brands, confirm each company's reporting approach.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Go! Sensitivities Grain-Free LID Venison (lowest within the evaluated subset of Petcurean formulas) | 3.58 | 16 | Petcurean · email Apr 21 2026 |
| Summit Farmstead Feast Pork Meal + Lamb Meal Large Breed Adult | 3.73 | 14 | Petcurean · email Apr 21 2026 |
| Go! Sensitivities Grain-Free LID Insect | 3.78 | 16 | Petcurean · email Apr 21 2026 |
| Gather Endless Valley Vegan | 4.00 | 15 | Petcurean · email Apr 21 2026 |
| Summit Farmstead Feast Pork Meal + Lamb Meal Adult | 4.02 | 15 | Petcurean · email Apr 21 2026 |
| Go! Digestion + Gut Health Chicken with Ancient Grains | 4.05 | 17 | Petcurean · email Apr 21 2026 |
| Gather Free Acres Organic Free-Run Chicken | 4.41 | 17 | Petcurean · email Apr 21 2026 |
| Now Fresh Grain-Free Turkey/Salmon/Duck Small Breed Adult | 4.52 | 18 | Petcurean · email Apr 21 2026 |
| Now Fresh Grain-Free Turkey/Salmon/Duck Adult | 4.67 | 19 | Petcurean · email Apr 21 2026 |
| Go! Weight Management + Joint Care Grain-Free Chicken | 4.69 | 19 | Petcurean · email Apr 21 2026 |
| Go! Skin + Coat Care Chicken with Grains | 4.78 | 20 | Petcurean · email Apr 21 2026 |
| Go! Skin + Coat Care Salmon with Grains | 5.05 | 20 | Petcurean · email Apr 21 2026 |
| Now Fresh Good Gravy Salmon Coated in Bone Broth | 5.14 | 21 | Petcurean · email Apr 21 2026 |
| Now Fresh Grain-Free Turkey/Salmon/Duck Senior | 5.30 | 19 | Petcurean · email Apr 21 2026 |
| Go! Digestion + Gut Health Salmon with Ancient GrainsExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.08 | 26 | Petcurean · email Apr 21 2026 |
| Go! Weight Management + Joint Care Grain-Free SalmonExceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.32 | 26 | Petcurean · email Apr 21 2026 |
Summit line Canada availability and remaining Go! Sensitivities LID flavour values — follow-up pending with Petcurean Apr 2026.
Instinct Pet Food
Instinct Pet Food OTC
Caroline, Instinct Customer Service · emails Apr 22–23 2026 · mg/Mcal calculated from confirmed DM values and kcal/kg
⚠ Instinct Limited Ingredient Diet formulas are counterintuitively higher in copper than Original Grain-Free kibble formulas among those evaluated. LID does not correlate with lower copper in this case. Owners choosing LID for sensitivity management should be aware of this finding; suitability should be assessed with a veterinarian.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | kcal/kg | Source |
| Original Grain-Free — Real Beef (lowest within the evaluated subset of Instinct kibble formulas) | 3.29 | 14.22 | 4,326 | Instinct · email Apr 22 2026 |
| Original Grain-Free — Real Chicken | 3.48 | 15.33 | 4,406 | Instinct · email Apr 22 2026 |
| Original Grain-Free — Real Salmon | 4.40 | 19.56 | 4,450 | Instinct · email Apr 22 2026 |
| Raw Boost — Chicken | 5.20 | 19.78 | 3,804 | Instinct · email Apr 22 2026 |
| Raw Boost — Salmon | 5.28 | 19.66 | 3,727 | Instinct · email Apr 22 2026 |
| Limited Ingredient Diet — SalmonHigher than Original GF kibble despite LID marketing; suitability should be assessed with a veterinarian. | 5.82 | 25.22 | 4,335 | Instinct · email Apr 22 2026 |
| Limited Ingredient Diet — LambExceeds EU/FEDIAF maximum despite LID marketing; suitability should be assessed with a veterinarian. | 6.44 | 27.78 | 4,315 | Instinct · email Apr 22 2026 |
| Freeze-Dried Raw — ChickenVery high — freeze-dried raw format with high organ inclusion. | 7.75 | 36.41 | 4,698 | Instinct · email Apr 22 2026 |
| Freeze-Dried Raw — LambVery high — freeze-dried raw format. | 9.03 | 39.36 | 4,357 | Instinct · email Apr 22 2026 |
| Freeze-Dried Raw — BeefHighest among evaluated Instinct formulas. | 9.24 | 41.88 | 4,534 | Instinct · email Apr 22 2026 |
Zignature
Zignature (Pets Global) OTC Partial — kcal pending
Lisa Kelly, Pets Global Inc. · email Apr 22 2026 · DM values only — kcal/kg and full lineup requested, awaiting nutritional team response · Copper from both natural ingredients and synthetic premix
mg/Mcal not yet calculated — kcal/kg pending from nutritional team. Values listed as mg/kg DM only. Zssential formula clarification pending.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Kangaroo (lowest confirmed among evaluated Zignature formulas) | Pending kcal | 15.30 | Zignature · email Apr 22 2026 |
| Zssential (multi-protein — clarification pending) | Pending kcal | 16.01 | Zignature · email Apr 22 2026 |
| Venison | Pending kcal | 17.83 | Zignature · email Apr 22 2026 |
| Turkey (formula 1) | Pending kcal | 19.41 | Zignature · email Apr 22 2026 |
| Turkey (formula 2) | Pending kcal | 20.34 | Zignature · email Apr 22 2026 |
Canidae
Canidae — Dry Food OTC
Lisa K, RVT — Customer Care Team Lead · Canidae Pet Foods · emails Apr 22–23 2026 · Values from typical average analysis · Pure Sky line discontinued
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | Source |
| Pure Farm to Bowl Wild-Caught Salmon & Sweet Potato (lowest within the evaluated subset of Canidae formulas) | 5.40 | Canidae · email Apr 22 2026 |
| All Life Stages Multi ProteinExceeds EU/FEDIAF maximum of 6.25 mg/Mcal; suitability should be assessed with a veterinarian. | 6.74 | Canidae · email Apr 22 2026 |
| All Life Stages Chicken & Ancient GrainsHighest among evaluated Canidae dry formulas. Exceeds EU/FEDIAF maximum; suitability should be assessed with a veterinarian. | 6.88 | Canidae · email Apr 22 2026 |
Canidae — Pure Treat Biscuits OTC
Lisa K, RVT — Customer Care Team Lead · Canidae Pet Foods · email Apr 23 2026 · Values confirmed as mg/Mcal (typical average analysis)
⚠ Data note: These mg/Mcal values (0.0017–0.0019) are substantially lower than any other treat or food product in this reference — approximately 1,000× lower than Pet Botanics Training Rewards and ~3,000× lower than Greenies by mg/Mcal. Ingredient lists for these treats are grain/plant-based with no organ meat and minimal copper supplementation, which may account for the very low values. Values are reported exactly as confirmed by Lisa K RVT and are flagged here for transparency. Independent verification is recommended before relying on these values for copper management decisions.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat (calc.) | kcal/treat | Source |
| Pure Treat Biscuits Salmon & Sweet Potato | 0.0019 | ~0.000038 | 20 kcal | Canidae · email Apr 23 2026 |
| Pure Treat Biscuits Duck & Chickpea | 0.0017 | ~0.000029 | 17 kcal | Canidae · email Apr 23 2026 |
Vital Essentials
Vital Essentials — Freeze-Dried Raw OTC
Michelle P., Vital Essentials Consumer Care · email Apr 22 2026 · Whole animal including organs and bone · Values provided as mg/Mcal directly by manufacturer
⚠ Vital Essentials formulas vary enormously by protein source due to organ meat inclusion. Chicken and Turkey are the lowest within the evaluated subset of formulas. Duck and Rabbit are extremely high — organ content drives copper up substantially.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | Source |
| Chicken (lowest within the evaluated subset of Vital Essentials formulas) | 3.7 | 15.0 | Vital Essentials · email Apr 22 2026 |
| Turkey | 3.7 | 14.0 | Vital Essentials · email Apr 22 2026 |
| Pheasant / Quail | 4.4 | 20.0 | Vital Essentials · email Apr 22 2026 |
| BeefSubstantially higher; suitability should be assessed with a veterinarian. | 8.94 | 39.0 | Vital Essentials · email Apr 22 2026 |
| Beef / Salmon | 9.0 | 41.0 | Vital Essentials · email Apr 22 2026 |
| Lamb / Whitefish | 10.1 | 49.0 | Vital Essentials · email Apr 22 2026 |
| Pork | 10.4 | 40.0 | Vital Essentials · email Apr 22 2026 |
| DuckVery high organ content; suitability should be assessed with a veterinarian. | 15.2 | 65.0 | Vital Essentials · email Apr 22 2026 |
| RabbitHighest among evaluated Vital Essentials formulas; suitability should be assessed with a veterinarian. | 16.1 | 66.0 | Vital Essentials · email Apr 22 2026 |
CaniSource
CaniSource Grand Cru & Homemade OTC
Jaime Hutchings, CaniSource · website data canisource.com · Quebec-based Canadian manufacturer · Freeze-dried raw format
⚠ Important data limitation: All values below are derived from guaranteed analysis minimums published on the CaniSource website. All formulas show the same copper minimum of 16.50 mg/kg as-fed — this is the declared floor, not the typical value. Actual copper content may be higher. A request for typical analysis values has been submitted to the manufacturer — this entry will be updated when confirmed. Values below are estimates only and should not be used for precise copper management decisions.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal (est. minimum) | mg/kg as-fed (GA min) | kcal/kg | Source |
| Turkey | ~3.44 est. | 16.50 (GA min) | 4,800 | canisource.com · Apr 23 2026 |
| Pork & Lamb | ~3.44 est. | 16.50 (GA min) | 4,800 | canisource.com · Apr 23 2026 |
| Red Meat | ~3.51 est. | 16.50 (GA min) | 4,696 | canisource.com · Apr 23 2026 |
| Chicken & Duck | ~3.58 est. | 16.50 (GA min) | 4,610 | canisource.com · Apr 23 2026 |
| Land & Sea | ~3.67 est. | 16.50 (GA min) | 4,500 | canisource.com · Apr 23 2026 |
| Homemade Grain-Free Chicken | ~3.86 est. | 16.50 (GA min) | 4,280 | canisource.com · Apr 23 2026 |
| Homemade Surf & Turf | ~3.86 est. | 16.50 (GA min) | 4,280 | canisource.com · Apr 23 2026 |
Performatrin (Pet Valu) OTC Partial — kcal pending
Katya R., Pet Valu Customer Care · email Apr 23 2026 · Canadian exclusive brand (Pet Valu) · DM values provided — kcal/kg follow-up sent Apr 23 2026
mg/Mcal not yet calculated — kcal/kg pending. Values listed as mg/kg DM and as-fed only.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/kg DM | mg/kg as-fed | Source |
| Ultra Grain-Free Foothills Recipe (lowest within the evaluated subset of Performatrin formulas) | Pending kcal | 15.9 | 15 | Pet Valu · email Apr 23 2026 |
| Prime Sensitive Skin & Stomach Salmon & Oatmeal Adult | Pending kcal | 17.0 | 16 | Pet Valu · email Apr 23 2026 |
| Ultra Grain-Free Original Large Breed Adult | Pending kcal | 18.2 | 17 | Pet Valu · email Apr 23 2026 |
| Prime Chicken & Rice Formula Adult | Pending kcal | 19.0 | 18 | Pet Valu · email Apr 23 2026 |
| Ultra Wholesome Grains Chicken & Brown Rice Adult | Pending kcal | 19.3 | 18 | Pet Valu · email Apr 23 2026 |
| Ultra Grain-Free Original Recipe | Pending kcal | 20.0 | 19 | Pet Valu · email Apr 23 2026 |
| Prime Chicken & Rice Formula Senior | Pending kcal | 20.0 | 18 | Pet Valu · email Apr 23 2026 |
| Ultra Wholesome Grains Healthy Weight Salmon Adult | Pending kcal | 21.4 | 20 | Pet Valu · email Apr 23 2026 |
Treats — Confirmed Values
All treat values are total copper per treat, calculated from manufacturer-confirmed mg/kg as-fed values and known or calculated treat weights. For biscuit treats, size matters significantly — a large biscuit can contain 10× the copper of a mini. Where mg/Mcal was not available for a treat product, the column is shown as — and mg/treat is the primary comparison metric. Treat mg/Mcal values are provided for context only and should not be compared directly to complete food mg/Mcal values given the intermittent nature of treat feeding.
Dentastix (Mars Petcare Canada) OTC
Mars Petcare Canada · Carlos · email Nov 4 2025 · Corrected from initial unit error, verified by registered technician · ~0.8–1.0 ppm as-fed confirmed basis
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat | mg/kg as-fed | kcal/treat · kcal/kg | Source |
| Original Medium | — | 0.023–0.029 | ~0.9 | 80 kcal · 2,755 kcal/kg | Mars Petcare Canada · Nov 4 2025 |
| Beef Medium | — | 0.021–0.026 | ~0.9 | 76 kcal · 2,870 kcal/kg | Mars Petcare Canada · Nov 4 2025 |
| Bacon & Chicken Large (dogs 40+ lbs) | — | 0.021–0.027 | ~0.9 | 74 kcal · 2,780 kcal/kg | Mars Petcare Canada · Nov 4 2025 |
Greenies (Mars Petcare Canada) OTC
Mars Petcare Canada · Carlos · email Apr 21–22 2026 · 14.84 mg/kg as-fed · 2,996 kcal/kg · 4.95 mg/Mcal · Original, Fresh, and Blueberry flavours share identical values
⚠ Greenies dental chews contain approximately 15× the copper per treat compared to a Dentastix medium, based on confirmed values. Owners managing copper-restricted dogs should consider treat frequency in total daily copper intake; suitability should be assessed with a veterinarian.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat | mg/kg as-fed | kcal/treat · kcal/kg | Source |
| Original / Fresh / Blueberry — Regular | 4.95 | 0.413–0.426 | 14.84 | 86 kcal · 2,996 kcal/kg | Mars Petcare Canada · Apr 22 2026 |
| Original / Fresh / Blueberry — Petite | 4.95 | 0.255–0.263 | 14.84 | 53 kcal · 2,996 kcal/kg | Mars Petcare Canada · Apr 22 2026 |
| Original / Fresh / Blueberry — Teenie | 4.95 | 0.120–0.124 | 14.84 | 25 kcal · 2,996 kcal/kg | Mars Petcare Canada · Apr 22 2026 |
Greenies Pill Pockets (Mars Petcare Canada) OTC
Mars Petcare Canada · Carlos · email Apr 22 2026 · Chicken, Hickory Smoke, and Peanut Butter flavours all share identical values · 3,070 kcal/kg · 0.81 mg/Mcal
Pill Pockets are substantially lower in copper than regular Greenies dental chews — approximately 6× lower by mg/Mcal. All flavours confirmed equivalent.
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat | mg/kg as-fed | kcal/treat · kcal/kg | Source |
| Pill Pockets — Tablet Size (all flavours) | 0.81 | ~0.008 | 2.49 | 10 kcal · 3,070 kcal/kg | Mars Petcare Canada · Apr 22 2026 |
| Pill Pockets — Capsule Size (all flavours) | 0.81 | ~0.019 | 2.49 | 23 kcal · 3,070 kcal/kg | Mars Petcare Canada · Apr 22 2026 |
Pet Botanics Training Rewards (General Mills) OTC
Christine M., Pet Botanics / General Mills · emails Apr 21 2026 · Complete — all metrics confirmed
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat (est.) | mg/kg as-fed | kcal/treat · kcal/kg | Source |
| Training Rewards Bacon | 1.62 | ~0.005 | 4.8 | 3 kcal · 2,960 kcal/kg | Pet Botanics · Apr 21 2026 |
| Training Rewards Beef | 1.76 | ~0.005 | 5.2 | 3 kcal · 2,960 kcal/kg | Pet Botanics · Apr 21 2026 |
| Training Rewards Mini Chicken | 2.04 | ~0.003 | 5.3 | 1.5 kcal · 2,600 kcal/kg | Pet Botanics · Apr 21 2026 |
| Training Rewards Chicken | 2.46 | ~0.007 | 6.4 | 3 kcal · 2,600 kcal/kg | Pet Botanics · Apr 21 2026 |
Crumps' Naturals OTC
Customer Service, The Crump Group Inc. · email Oct 21 2025 · Full product line expansion request sent Apr 21 2026 — awaiting R&D response
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat | mg/kg as-fed | Source |
| Plaque Busters Original (lowest within the evaluated subset of Crumps' formulas) | — | 0.021 | — | Crumps' · email Oct 21 2025 |
| Plaque Busters — other flavours (all fall within range) | — | 0.021–0.045 | — | Crumps' · email Oct 21 2025 |
| Plaque Busters Kelp & Mint (highest within the evaluated subset of) | — | 0.045 | — | Crumps' · email Oct 21 2025 |
| Sweet Potato Chews | — | 0.06 | — | Crumps' · email Oct 21 2025 |
Wellness / Old Mother Hubbard OTC
Maryann, Wellness Pet Co. · email Apr 20 2026
⚠ Reference Data Only — Not a Recommendation or RankingValues may vary and should be interpreted with veterinary guidance.
| Product | mg/Mcal | mg/treat | mg/kg as-fed | Source |
| Soft WellBites — Beef & Turkey (~8 kcal, ~2.5g) | — | ~0.006 | 2.27 | Wellness · Apr 20 2026 |
| Soft WellBites — Lamb & Salmon | — | ~0.006 | 2.58 | Wellness · Apr 20 2026 |
| Soft Bites Training Treats — Lamb & Salmon | — | ~0.006 | 2.44 | Wellness · Apr 20 2026 |
| Soft WellBites — Turkey & Duck | — | ~0.008 | 3.03 | Wellness · Apr 20 2026 |
| Soft WellBites — Chicken & Lamb | — | ~0.008 | 3.23 | Wellness · Apr 20 2026 |
| Old Mother Hubbard Classic Original — Mini (~3.5g) | — | ~0.020 | 5.82 | Wellness · Apr 20 2026 |
| Old Mother Hubbard Classic P-Nuttier — Mini (~2.9g) | — | ~0.019 | 6.45 | Wellness · Apr 20 2026 |
| Old Mother Hubbard Classic Original — Small (~10g) | — | ~0.059 | 5.82 | Wellness · Apr 20 2026 |
| Old Mother Hubbard Classic P-Nuttier — Small (~10g) | — | ~0.064 | 6.45 | Wellness · Apr 20 2026 |
| Old Mother Hubbard Classic Original — Large (~40g)Large biscuits contain ~10× the copper of mini size. | — | ~0.232 | 5.82 | Wellness · Apr 20 2026 |
| Old Mother Hubbard Classic P-Nuttier — Large (~40g)Large biscuits contain ~10× the copper of mini size. | — | ~0.257 | 6.45 | Wellness · Apr 20 2026 |
Contacted — Responded but No Data Provided
| Brand | Status | Notes |
| Hill's Science Diet (OTC) | No data | Responded Apr 16 2026 — stated specific nutrient levels are not available to the Consumer Affairs team for OTC products. Hill's prescription (Rx) l/d copper values are publicly available; OTC values were not provided. |
| Merrick | No data | Responded Apr 2026 — stated products have similar copper values but did not provide specific data; referred to Purina veterinary support. Merrick is owned by Nestlé Purina. |
| Bocce's Bakery (treats) | No total | Responded Apr 18–20 2026 — copper is not part of standard guaranteed analysis for treats. Provided ingredient-level estimates only (oat flour: ~0.011 mg/treat; barley flour Small Batch: ~0.017 mg/treat). Total finished-product copper not available. Specialist team confirmed no total copper testing performed on treats. |
| Dr. Marty (Nature's Blend) | No data | Responded Apr 2026 — formulation details are proprietary and were not disclosed. |
| Open Farm (treats) | No data | Responded Apr 22 2026 — treat products are intended for intermittent or supplemental feeding only; full nutritional breakdown not provided for treats. Request forwarded for future consideration. |
| Purina Pro Plan Veterinary Diets | No Rx diet | Confirmed Apr 23 2026 (Megan CVT, Purina Senior Veterinary Product Advisor) — no copper-restricted veterinary diet available in the Purina Pro Plan Veterinary Diets lineup. |
Pending Responses
| Brand | Status | Notes |
| Zignature — kcal/kg + full lineup | Sent to nutritional team | Full data request sent Apr 23 2026 to Lisa Kelly / Pets Global nutritional team. |
| Performatrin — kcal/kg | Follow-up sent | kcal/kg follow-up sent Apr 23 2026 to Katya / Pet Valu. |
| Canidae treats — unit clarification | Clarification sent | Values of 0.0017–0.0019 appear to require clarification — mg/Mcal vs mg/treat — sent Apr 23 2026 to Lisa K RVT. |
| CaniSource — typical analysis | Follow-up sent | Typical analysis (vs GA minimum) follow-up sent to Jaime Hutchings. Website shows GA minimums only. |
| Petcurean — LID remaining flavours + Summit Canada | Follow-up sent | Additional LID flavours and Summit Canada availability follow-up sent to Emily Apr 22 2026. |
| Instinct — Raw Boost Mixer kcal/kg | Pending | kcal/kg for Raw Boost Mixers not yet provided — needed to calculate mg/Mcal for treat section. |
| Crumps' / Caledon Farms — full line | R&D in progress | Both brands owned by The Crump Group Inc. Full line expansion sent Apr 21 2026. |
| Farmina N&D | Overdue | Contacted Apr 14 2026. Follow-up sent Apr 22 2026. Label shows 15.8 mg/kg added copper only — total unconfirmed. |
| Stewart | Sent Apr 20 | Awaiting response. |
| Boréal, Canada Fresh/PetKind, Sunday Pets, Rollover, Northern Biscuit, Horizon, Canadian Naturals, Stella & Chewy's | Sent Apr 18–19 | No replies received. |
| Zuke's, Milk-Bone, PureBites, Charlee Bear, Darford, Benny Bully's, Bil-Jac | Sent Apr 18 | Treat batch — no replies received. |
Data Notes & Methodology
Data Scope
This reference contains only values reported as provided by manufacturers via direct email correspondence or their official publications. No survey-based, community-reported, or unverified data is included. All source attributions include manufacturer name and month/year of confirmation. Absence of data for a given product or brand does not imply higher or lower copper content.
Note: Companies vary in how they report copper values. Some disclose only the supplemented amount while others report both supplemented and naturally occurring copper. Where known, the reporting approach is noted in the brand section. Petcurean explicitly reports both; others may not.
mg/Mcal Conversions
Where only mg/kg DM was provided by manufacturer, mg/Mcal was calculated using published kcal/kg caloric density per product. Values marked ~ are calculated estimates. Where kcal/kg was not available, no mg/Mcal is stated rather than estimate.
Wet Food / High-Moisture Products
For canned wet food and similar high-moisture products, as-fed copper values appear lower than dry or air-dried products due to dilution by moisture (~74–84% water). DM values and mg/Mcal are the appropriate comparison metrics across formats. Do not compare as-fed values between wet and dry products directly.
Guaranteed Analysis vs Typical Analysis
Guaranteed analysis values represent declared minimums or maximums — they are regulatory floors or ceilings, not actual measured content. Typical analysis values represent averaged laboratory measurements and are more useful for precise copper management. This reference uses typical analysis values wherever available. Where only guaranteed analysis is available, this is clearly noted and estimates are labeled accordingly.
Treat mg/treat Calculations
Calculated from confirmed mg/kg as-fed values and treat weights derived from published kcal/treat ÷ published kcal/kg. Values marked ~ are estimates. For biscuit treats, the same mg/kg value produces vastly different per-treat copper amounts depending on biscuit size; always use the per-treat value for the specific size fed.
Breeds at Elevated Risk for Copper-Associated Hepatopathy
Evidence-Based Risk Stratification
Well-established predisposition (strong, consistent peer-reviewed evidence):
Bedlington Terrier — COMMD1 mutation; strongest genetic evidence for primary copper storage disease [1]. Labrador Retriever — hepatic copper accumulation and genetic modifiers (ATP7A/ATP7B) well documented [2] [3]. Doberman Pinscher — chronic hepatitis with copper involvement [4].
Moderately established (consistent reports, often multifactorial or secondary):
West Highland White Terrier — breed-associated copper accumulation [5]. Dalmatian — hepatic copper accumulation [6]. Skye Terrier — chronic hepatitis with copper storage [7]. American Cocker Spaniel — chronic hepatitis patterns [8].
Limited or inconsistent evidence (occasional reports, weak or mixed data):
Dachshund — reported in broader chronic hepatitis cohorts; no strong breed-specific causal data. Clumber Spaniel — sporadic case reports only.
Anecdotal / occasionally reported, not widely accepted in authoritative lists:
Welsh Corgi (Pembroke & Cardigan) — mentioned occasionally in case reports and clinical discussions; no peer-reviewed consensus establishing predisposition.
CAH can develop in any breed or mixed-breed dog, particularly with increased dietary copper exposure [9] [10] [11]. The absence of a breed from the above list does not eliminate risk. Consult a veterinarian for breed-specific guidance. This list is not exhaustive and reflects the state of published evidence at the time of compilation.
References include peer-reviewed veterinary literature (PubMed-indexed) examining breed predisposition, hepatic copper accumulation, and genetic factors associated with canine copper-associated hepatopathy.
References
[1] van De Sluis et al. (2002).
Identification of a new copper metabolism gene by positional cloning in a purebred dog population. PubMed 12469120
[2] Dirksen et al. (2012).
Hepatic copper accumulation in Labrador Retrievers. PubMed 22472581
[3] Fieten et al. (2016).
The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers. PubMed 27067352
[4] Spee et al. (2005).
Copper metabolism and oxidative stress in chronic inflammatory and cholestatic liver diseases in dogs. PubMed 16145170
[5] Thornburg et al. (1996).
Copper toxicosis in West Highland White Terriers. PubMed 8689697
[6] Webb et al. (2002).
Hepatic copper accumulation in Dalmatians. PubMed 12465760
[7] Haywood et al. (1988).
Chronic hepatitis in Skye Terriers. PubMed 3390171
[8] Strombeck et al. (1988).
Chronic hepatitis patterns in American Cocker Spaniels. PubMed 3390168
[9] Center et al. (2014).
Diagnosis and management of copper-associated hepatopathy. PubMed 24703606
[10] Watson (2004).
Chronic hepatitis in dogs: a review. PubMed 15144104
[11] Dirksen & Fieten (2017).
Canine copper-associated hepatitis. PubMed 28224990
Changelog
Version History
Draft 1.0 — April 23, 2026
Initial working draft. Brands with confirmed data: Royal Canin (Rx + OTC), Honest Kitchen (Wholemade + Clusters), Nature's Logic Distinction, Voyager, Open Farm, ORIJEN, ACANA (kibble + freeze-dried), Wellness (50+ formulas), IAMS, Purina Pro Plan (all 8 formulas), Blue Buffalo, Diamond/Kirkland/Taste of the Wild, Primal Pet Foods (full line), ZIWI Peak (Air-Dried, Steam & Dried, Canned), Nutrience (full 10-formula lineup), FirstMate (range/average only — no per-formula), Fromm Family (Classic dry, Gold dry, Gold Coast dry, Four-Star dry, Heartland Gold dry, Nutritionals dry, wet/canned full lineup, Bonnihill Farms frozen), Petcurean (Now Fresh, GO!, Gather, Summit), Instinct Pet Food (kibble, freeze-dried, LID, Raw Boost Mixers), Zignature (partial — kcal pending), Canidae (3 food formulas — treats pending), Vital Essentials (full freeze-dried lineup), CaniSource (GA minimum only — pending), Performatrin (8 formulas — kcal pending).
Treats confirmed: Dentastix, Crumps' Naturals, Greenies (all sizes + Pill Pockets), Pet Botanics, Wellness/Old Mother Hubbard.
Responded — no data: Hill's Science Diet OTC, Merrick, Bocce's Bakery, Dr. Marty, Open Farm treats, Purina Veterinary Diets.
Draft 1.0 rev 1 — April 24, 2026
Data additions: Canidae treats complete (Pure Biscuits Salmon & Sweet Potato + Duck & Chickpea — flagged unusually low, independent verification recommended). Breeds section expanded with full evidence-tiered citations and 11 PubMed-indexed references.
Document structure: "How to Use This Reference" section added near top. Table-level warning bar added to all data tables. All "lowest/highest among evaluated" language standardized to "within the evaluated subset." RC OTC header updated to remove implied market-wide comparison.
Disclaimer: "not a product comparison, ranking, or recommendation guide" added as opening line. "and educational" added to purpose statement. "and may vary" added to values sentence. "and discretion" added to risk sentence. Liability clause strengthened.